This book is developed in a lucid manner for readers to grasp information about the role and potential of microbes in sustainable agriculture & computational strategies associated with it. Present volume focuses on advancements of microbial research in increasing agricultural productivity and sustainability viz. plant growth promotion by rhizobacterial biostimulants, endophytes, actinobacteria, arbuscularmycorrhizal fungi and biocontrol. Present day research is focused on role of soil microbe’s in agriculture, diazotropic & azotobacterial N2 fixation, PGPR etc. However, there is dearth of information on bioremediation of agrochemicals, biocontrol etc. This book is a compilation of research advances in both the aspect from eminent experts around the globe. In addition, in-silico mediated understandings of plant pathology, use of artificial neural networks in phytopathogen prediction, computational approaches in enhancing secondary metabolites production will be beneficial to professionals and academicians for sustainable agriculture. This volume will be very helpful for the students, teachers, professionals, and scientists concerned in agricultural production, food security, soil microbiology, agricultural biotechnology, and computational techniques.