Social work practice has evolved to meet the needs of the time, the problems that are present, and the knowledge and skills available. Given the more recent rapidly changing stressful environments, political, economic, demographic, sociocultural, and ideological change has affected how practice is defined. Now it is even more essential for there to be innovative theoretical concepts and intervention strategies to support current practice. This textbook addresses today’s context of social work practice that needs to deal with the complexity of personal and social relationships, the continuing historical flux of the times, and the constant anxiety or “threats and pulls” of daily life. The text is based on the idea that social work practice requires a research and theoretical base that allows practitioners to build on a client’s ability to persist in the face of life’s challenges and to proceed positively with life events. The Resilience-Enhancing Stress Model (RESM) is an outgrowth of the profession’s interest in strength-based person-environment approaches - grounded in generalist social work practice that offers a range of intervention practice methods with diverse individuals, families, groups, organizations, and communities. RESM was developed to provide the skill set for working with clients and constituencies across the individual-family-community configuration during times of distress. It also can be a welcomed addition to social work practice with people undertaking life transitions and overcoming disruption to individual, family, and community function. Topics explored include: An Evolving Resilience-Enhancing Stress Model Interviewing to Promote Resilience Among Marginalized Populations Co-creating a Grand Narrative: The Intersection of Individual, Family, and Community Practice Connecting Communal Living, Ecology, and Resilience A Resilience-Enhancing Stress Model: A Social Work Multisystemic Practice Approach is a timely text for human behavior and practice methods at the generalist or advanced generalist levels in social work. It can also be used at the doctoral level of social work education depending on the professor’s attention to the depth of theoretical concepts. Practitioners in the field may find the contents useful to their professional enrichment.